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Deaths Suspected or Confirmed as Being Caused by Rimadyl Toxicity

12/11/99 Death #72: 11-Year-Old Rottweiler Reacts after Three Doses of Rimady; Dies Four Days after Initial Dose
Breed: Rottweiler (male, "Bubba")
Age: 11 years
Reason for Rimadyl rx: muscle damage from dog fight
Dog's weight and dosage taken: 118 lbs, 125 mg twice daily
When reaction occurred following initial dose: 24 hours
Symptoms: severe bloating and passing of gas, inappetance, inability to defecate or urinate, increased thirst, lethargy
Date of death: 12/11/99
Did vet seem informed about side effects and inform you?: My vet, yes; the emergency vet, no
Remarks on Dog's Rimadyl Experience: "My Rottie had been on glucosamine/chondroitin for about a year for his severe arthritis. It was a tremendous help to him. However, on 12/7/99, he was attacked by another much younger dog and suffered intense muscle damage and showed symptoms of lameness. The emergency vet (not our regular vet who advised me against Rimadyl because of the potential side effects to the digestive system) prescribed Rimadyl twice a day for 7 days along with antibiotics. After only 4 doses of Rimadyl, Bubba quit eating (even his favorite: peanut butter!), became extremely distended (his stomach sounded like a ripe watermelon when plucked), refused to urinate or defecate, passed tremendous amounts of gas, and drank unusual amounts of water. After he had been on Rimadyl for only 24 hours, I found that he had urinated on his bed and was just lying in it. I called my personal vet to report these symptoms. He advised that I stop Rimadyl immediately and closely monitor my dog. He voluntarily went outside once, but that was the last time he even attempted to get up on his own. He continued to refuse food and water, eventually lost control of his bladder, and simply stopped breathing. This occurred 4 days after his first dose of Rimadyl."
abjw@mindspring.com

12/6/99 Death #71: Vital Information/Advice in This Report!!
(Editor's note: The name of the prescribing veterinarian mentioned in this report has been modified to avoid libel.)
Breed: Lab/Newfoundland (male, "Charlie")
Age: 8 years
Reason for Rimadyl rx: arthritis in one paw
Dog's weight and dosage taken: 95 lbs / 75 mg once daily
When reaction occurred following initial dose: 3 days
Symptoms: lethargy, diarrhea, vomiting
Date of death: October 1999
Was vet informed about side effects and did he inform you?: No, to both
Remarks on Dog's Rimadyl Experience: "My dog Charlie was eight years old. He was a Lab cross, and he was healthy except for some arthritis. We were treating this condition with aspirin. One weekend, Charlie was playing with other dogs -- running, etc. The next two days we noticed a pronounced limp. I spoke with a veterinarian that we had previously seen for a routine check-up -- Dr. X -- about this and was told that a new drug with FDA approval was put on the market and was a good drug for treating arthritis. I was informed about the one in 10,000 dogs having an adverse reaction.

"After getting a one-week free sample, we started Charlie on this new drug called Rimadyl. We noticed a marked improvement in his walk within 24 hrs. However, within three days of using Rimadyl, we noticed that Charlie was not eating much, and had to go outside more often. Then, on the third day, he started vomiting.

"My wife took Charlie back into the vet; he drew some blood, stated he was dehydrated, gave him an IV of fluid and sent us home. Charlie was to go on a soft bland diet. Dr. X called the next day and wanted another blood sample, as he was not satisfied with the results he had received. There was some concern about liver enzymes and a low blood count. So, again, Charlie was taken to Dr. X for a blood sample.

"After getting the results back, it was decided that we should take our Charlie to the University of Minnesota clinic for a liver biopsy and to flush his system, as there was a toxic reaction starting. On Tuesday, 19 October, the liver biopsy was completed and Charlie recovered from that, in fact Dr. Robert Hardy at the University of Minnesota, said he was up, tail wagging and wanted out of his cage. Dr. Hardy, said that he felt Charlie had some liver damage and but should respond to treatment. He was fine during rounds and then, 10 minutes later, a veterinary student went by his cage and he was dead.

"They tried to resuscitate him, but to no avail; he was gone. It was Dr. Hardy’s opinion that he aspirated and died. Then the results of the liver biopsy came back, showing marked similarities between other dogs treated with Rimadyl and his results. He had moderate to severe liver damage and a toxic reaction, destroying his liver; the kidneys were starting to show signs of failure, too.

"On Monday, Oct 24th, I spoke with Dr. Hardy again, and he stated that they just took in a German Shepherd exhibiting the same signs of Rimadyl toxicity that our dog Charlie had.

"After we did further research into the drug Rimadyl and the parent company (Pfizer), we found their own studies show that 25% of all liver failures, which may result in fatal reactions, were in Labs or Lab crosses. No other results were specified for other breeds. In fact, it was only tested on 297 dogs per published information. Isn’t this a little too small a sampling to decide if a drug is safe? Is Pfizer in truth now conducting field tests on consumers' dogs? I would like to know before anyone else has to lose their friend.

"We have spoken with many veterinarians about this drug; some like it, others do not, but all agree that this kind of toxic reaction in a short amount of time was odd.

"Also, I would like to make note that not all veterinarians are up to speed on this drug. Dr. X is one of them. At no time were we offered a liver function test for Charlie, nor were we even offered the informational brochure on Rimadyl. And, as of November 2, 1999, Dr. X has only contacted us to offer an autopsy and to stop by my wife’s work prior to receiving the liver biopsy to express his sympathies and to again state that he did not think it was Rimadyl.

"Well, we have proof that it was in fact Rimadyl that caused Charlie's death. There are laboratory test results and a letter of conclusion from Dr. Robert Hardy, DVM, Internal Medicine, University of Minnesota Veterinary Professor.

"I am sorry to take your time with such a sad story, but this drug is not safe. Please pass this along to anyone you know, and, if they have a dog on Rimadyl, please have them get a liver function test to check for damage. (It may be the only thing to save their life; do this before they start on Rimadyl and during treatment.)

"It has also been noted by several veterinarians that the recommended dosages are too high and that the pills should be cut in half.

"Anyone who knows us knows how much we care for our animals. No one needs to go through this again. Please feel free to give any interested person our E-mail address. We would be glad to share more details about this."
itdog@wadena.net

11/16/99 Death #70: Basset with History of Bleeding Ulcers Is Placed on Rimadyl and Dies
Breed: Basset (male, "Bubba")
Age: 9 years
Reason for Rimadyl rx: arthritis in one paw
Dog's weight and dosage taken: 57 lbs / 100 mg daily
When reaction occurred following initial dose: 8 months
Symptoms: vomiting blood, bloody discharge from rectum
Date of death: 9/22/99
Was vet informed about side effects and did he inform you?: He had NOT been well advised by Pfizer
Remarks on Dog's Rimadyl Experience: "My dog had a propensity for bleeding ulcers since the time he was rescued, four years ago. He was a wonderful dog right up until he died."
bassets@iinc.com

11/4/99 Case #79 Update/Death #69: Megaesophagus a Factor in the Death of "Patches"

"At my last writing, Patches, my 13- year-old mixed breed had still been vomiting. The initial reason for Rimadyl was for mild arthritis. He weighed approximately 58 pounds at the time. I gave him 10mg twice a day. The vet finally told me that a scope would be necessary. I called the the Pfizer Company and they agreed to pay for the scope. The scope found lesions in his stomach and esophagus. They tested for cancer. None was found. They then prescribed Prednisone and Tagamat to hopefully soothe the sores. He continued to drop weight and vomit. I took him to the vet and he has been on an IV for two days. They vet then checked to see if he had megaesophagus. He does. I'm told this is rare in older dogs. He had never had the problem before. He is now developing pneumonia. I'm going to bring him home for a couple of days and then have him put to sleep. It has been a very painful experience that I hope not many more people will have to go through. At the last weigh-in Patches was 37 pounds. He got to starve to death."
Carrol.Dandoy@HILL.af.mil

10/25/99 Death #68: Dog Takes Rimadyl for Years; Shows Symptoms of Toxicity at Death
Breed: Shar-Pei (male, "Shin")
Age: 10 years
Reason for Rimadyl rx: arthritis in rear hips
Dog's weight and dosage taken: 55 - 60 lbs / 50 mg twice daily
When reaction occurred following initial dose: No immediate reaction - took several years to slowly damage and kill
Symptoms: increased thrist, uncontrollable vomiting, vomiting green bile, blood in urine just before death, white cell counts from blood test were off the chart, diarrhea, weight loss, bloated look
Date of episode: April 14, 1999
Vet informed about side effects: No, nothing was mentioned about side effects
Remarks on Dog's Rimadyl Experience: "Rimadyl seemed to be the answer to my dog's arthritis problem. Getting up and walking was very painful for him. He started on Rimadyl and seemed to be able to do things (like play with the other dogs) that he couldn't do before. He took Rimadyl for several years. During this time, the vet prescribed steroid (predinzone) for his skin allergies several different times. I asked if it was safe to take both the steroid and Rimadyl; he said that it was. In the last year, his health started to change but not enough for concern; it was just the little things that you notice that most people wouldn't. His attitude was grouchy towards anyone who disturbed his rest, etc. In the end, I noticed an increased thirst and also blood in his urine; this happened about one month before he was gone. In the last two weeks, his appetite decreased and he started to lose weight and started to vomit more and more often. I couldn't get an appointment with the vet until his last week, at which time I knew things were very serious. The blood work showed nothing except an extremely high white cell count. He was on IV fluids because he wasn't eating at all. His last day, he started vomiting uncontrollably (it was green bile until the last - then it was bloody); he collapsed and convulsed. My vet told me he thought his intestines had ruptured and it looked like they had been filled with fluid (infection) and there was nothing more that could be done for him. He never once suspected Rimadyl. After reading other reports, I believe it was a slow torture which finally took his life."
bvogel3@visteon.com

10/23/99 Death #67: Vet Tech Reports Death of Six-Year-Old Lab Mix from Taking Rimadyl Following Orthopedic Surgery
Breed: Lab Mix (male, "Shadow")
Age: 6 years
Reason for Rimadyl rx: for discomfort after orthopedic surgery
Dog's weight and dosage taken: not specified
When reaction occurred following initial dose: 2 weeks
Symptoms: loss of appetite, vomiting, lethary, extreme jaundice
Date of death: October 1999
Did vet seem informed & provide information about side effects? Vet was informed but did not provide information about side effects to dog's owner
Remarks on Dog's Rimadyl Experience: "This dog died because of this drug."
Cooter@bellatlantic.net

10/22/99 Death #66: Dog Dies in a Pool of Bloody Diarrhea after 45 Days on Rimadyl; No Side Effects Warning Given by Vet
Breed: Golden Retriever (female, "Sandy")
Age: 13 years
Reason for Rimadyl rx: arthritis
Dog's weight and dosage taken: 55 lbs (dosage not specified)
When reaction occurred following initial dose: about 45 days
Symptoms: incontinence; initial dizziness followed by lethargy; presumed liver failure and/or internal bleeding
Date of death: March 1999
Did vet seem informed & inform you about side effects? No
Remarks on Dog's Rimadyl Experience: "Sandy, our 13-year-old Golden, was in great health, but her rear leg was slowing her down a bit. The vet said it was the start of arthritis and suggested we put her on Rimadyl. Rimadyl seemed to help, but, about a month later, she urinated in the hallway -- her first mistake since she was a puppy. She became listless and had more 'mistakes' over the next month and then started to go downhill fast in the last week. During that time, she could no longer follow us around and could barely get up. On her last day, when we got up, I found her in the family room in a pool of dark molasses-like fluid stool, barely alive. I had to have her very sadly put down that day, six months ago. I couldn't understand why she went so rapidly. Now I know."
tmoore@cordblood.com

9/23/99 Death #65: Assistance Dog Dies after Rimadyl Reaction; No Side Effects Warnings Given by Vet
Breed: Irish Wolfhound ( Male, "Casey")
Age: 8 1/2 years
Reason for Rimadyl rx: Back strain
Dog's weight and dosage taken: 126 lbs (dosage not specified)
When reaction occurred following initial dose: Began panting about the second day
Symptoms: Seemed to be in a lot of pain; incontinence, aggressiveness, listlessness, restlessness, panting, vomiting, fast hearbeat, inappetance
Date of death: 4/02/99
Did vet seem informed & inform you about side effects? No; the vet said nothing at all
Remarks on Dog's Rimadyl Experience: "Casey had had a couple of other episodes with back strain earlier in his life. When he had this one at the end of March, I took him to the vet's office, where they did blood tests. They said he was in perfect shape. They prescribed prednisone, and said it should help the pain. He still was hurting after a day, however, so the vet said she would give him Rimadyl. I was told nothing about this medication except that it would help. When taking the Rimadyl, at first he seemed able to rest a bit better, but, after a couple of days, he was worse. He was panting hard and very restless, and started being incontinent. I stopped the prednisone because previously a shot of it had caused incontinence. I stopped it at about the time he began taking Rimadyl, but the incontinence didn't end, and Casey just kept panting; he was still drinking and eating, however. Then I noticed he had become aggressive with other dogs; I thought it was because he was in pain. He couldn't get comfortable, no matter how he tried, and the more Rimadyl he took, the worse he got. Then, he stopped eating and drinking. The final night he went to the door and asked to go out. He went to the car and looked at me with so much pain that I took him to the vet immediately. The vet put him under anesthesia because his heart was racing so fast. He was then given an IV and entubation for the x-ray to see what the problem was. Nothing showed. The vet then thought it was a tumor in his spine, because he was in so much pain and it came on so fast. I was told to make an appointment for Monday morning for a test that was a thousand dollars. I had to travel to Ohio to a specialist for it. I received a call two hours later that he was dead. I almost died myself. Casey was my shadow, my best friend, and my love. He helped his disabled person off the couch everytime I asked him. How did a perfectly healthy, young-acting dog die from a strained back that he had completely recovered from twice before? I guess I believed he must have had the tumor, and it had to be cancer, so we buried him. After reading about Darlene's dog (Case #45), I almost went mad. Casey died like the other dogs! I am so upset. I hold Pfizer responsible for this. I thought I was helping him. I would never have put his life in danger; he meant too much to me. I will have the memory of his face in that awful pain forever."
Ravenwoof@aol.com

9/23/99 Death #64: Side Effects Warnings Not Given; Dog Loses Functions and Dies Slowly Over Four Months
Breed: Labrador Retriever (male, "Khan")
Age: 13 years
Reason for Rimadyl rx: arthritis
Dog's weight and dosage taken: not specified
When reaction occurred following initial dose: 5 months
Symptoms: loss of eyesight, loss of bladder control, confusion, labored breathing, inability to walk, inappetance
Date of death: 9/15/99
Vet Informed about side effects? Not sure; vet also had his own dog on Rimadyl who had to be put down
Remarks on Dog's Rimadyl Experience: "I took Khan to the vet in late February 1999 for a heartworm test. While I was there, I asked the vet about soreness in his leg; the vet said it was arthritis. I had been giving him aspirin, which seemed to help, but the vet said Rimadyl would work better, so I put him on it. He seemed fine the first couple of months; then he slowly started to lose control over his bodily funtions over the next four months. I watched my dog slowly die, never supecting it was the medicine. The last two weeks were so bad for him, we finally had to put him down. Three days later I found these reports. I was shocked and mad. I have sent copies to my vet. I only hope it helps someone else. I feel so bad for what this did to my Khan. We miss him, and his eight-year-old son does, too."
jerose@centuryinter.net

8/31/99 Death #63/Update to Case #68: Dog Is Euthanized Following Liver Toxicity
Breed: Spaniel/Border Collie mix (female, "Jipsy")
Age: 12 years
Reason for Rimadyl rx: arthritis
Dog's weight and dosage taken: 55 lbs; 50 mg/2x daily; subsequently reduced to 25mg every other day
When reaction occurred following initial dose: 2 1/2 years; initially prescribed on 2/28/97
Date of episode: several days
Symptoms: liver toxicity detected by blood tests
Date of death: 7/14/99
Remarks on Dog's Rimadyl Experience: "Jipsy's kidneys had failed; she could not retain any food or produce any urine. She was dying before my eyes. Her collapse was attributed to complications from liver toxicity, which was confirmed by blood tests. 7/10/99 blood test measured alk phos - 7440 (normal range 5-131), creatinine- 2.8 (normal range 0.5-1.6). 7/14/99 levels were alk phos - 10490, creatinine - 8.6. She was euthanized on July 14. Autopsy determined kidneys appeared nearly normal; liver was grainy and gristly with scar tissue, but contained no apparent tumors."
kbheaton@swbell.nett

9/21/99 Death #62: First Vet Diagnoses Pancreatitis; Vet #2 Correctly Diagnoses Rimadyl Toxicity, but It Is Too Late
Breed: Shepherd/Collie mix (male, "Rosco")
Age: 7 years
Reason for Rimadyl rx: slight inflammation in neck and head causing pain in front legs
Dog's weight and dosage taken: 65 lb. 50mg 2x daily
When reaction occurred following initial dose: 3 days
Symptoms: vomiting, inappetance, inability to keep water down, progressed to jaundice, liver toxicity, pancreatitis and renal failure
Date of death: September 19, 1999, 5:05 p.m.
Vet informed about side effects and informed you? Absolutely not; in fact, I wasn't even told Rimadyl was being prescribed. The vet said, "We'll give him an anti-inflammatory."
Remarks on Dog's Rimadyl Experience: "The first vet poo-pooed my Rimadyl theory when Rosco first got sick. I was told it was acute pancreatitis, most likely caused by overindulgance in fatty foods. The day he was prescribed the Rimadyl, complete bloodwork was done. All levels were normal. Ten days later (after having been on Rimadyl for only 3 days), his Bilirubin level was sky high (9.0, normal level is 0.1 to 0.3) All liver enzyme, ALT, AST were also through the roof, along with lipase and amylase. He was admitted to hospital (first vet) and treated with IV fluid. Spent one night then sent home, asked to come back next day, then sent home, then finally admitted and kept for 5 days. Sent home and quit eating 3 days later. Was totally disgusted with vet #1 and found vet #2, who suspected Rimadyl almost immediately (even before I had voiced my concerns). He admitted Rosco to his hospital and treated him for renal failure. I hoped and prayed Rosco would pull through, but he did not make it. My personal goal at this point is to ensure that no other pet owner or pet suffers this way. I found out too late that the only miracle about Rimadyl is that it's a miracle if your dog survives it."
oclair@steptools.com

9/10/99 Death #61: Toxic Symptoms Appear Suddenly; Dog Dies within 18 Hours
Breed: Standard Poodle (male, "Torbec's Animation Chenook Corley")
Age: 11 years, 8 months
Reason for Rimadyl rx: seemed to have pain in hips when trying to stand up on back legs
Dog's weight and dosage taken: about 80 lb, 1 tablet daily; later increased to 2 tablets daily (Note: Dog was not overweight, just very large -- 30 inches at the shoulder)
When reaction occurred following initial dose: not specified
Symptoms: no outwardly observable reaction until sudden appearance of blood in urine, stool and vomit
Date of death: August 31, 1999
Vet informed about side effects: Either he did not know or was playing dumb to protect himself.
Remarks on Dog's Rimadyl Experience: "We took Chinook to the vet immediately when blood appeared in his urine, stool, and vomit. He died about 18 hours after the symptoms first appeared. The autopsy showed very little wear and tear on his hips. In fact, the vet stated that they looked very good for a dog his age. However, his liver, kidney, and pancreas were severely damaged. The vet stated that he didn't know how the dog had lived that long with that condition. The fact is he had not had the condition very long: a blood test two months prior to his death indicated that all his organs were functioning normally, except for his liver, on which the reading was 20 points above normal. The vet said that was very good for a dog his age. It is my belief that the Rimadyl was doing cummulative damage all along and simply did not show itself until the last moment, when it was much too late to do anything about it."
corley.paul@worldnet.att.net
Additional Remarks: "Is any legal action being taken now to get this killer off the market? All of Chenook's siblings are still alive and in good health. I'm sure many are feeling the same heartbreak I am. It seems to me that many great dogs have been made to suffer or die because of Rimadyl. Something must be done to insure this drug is removed from the market and the manufacturer does not profit from the damage they have done."
corley.paul@worldnet.att.net

8/11/99 Death # 60: Disclaimer in Rimadyl Ad Is Too Little, Too Late for Six-year-old Savannah
Breed: Black Lab (female, "Savannah")
Age When Rimadyl Reaction Occurred: 6 years
Reason for Rimadyl rx: joint stiffness
Dog's Weight & Dosage: 90 lbs; dosage not specified
When reaction occurred following initial dose: 4-6 weeks
Symptoms: lethargy, general malaise, loss of appetite
Vet informed about side effects: "I was told there were no serious side effects; the only downside to this drug was its cost.  I was told I could have as much as I needed whenever I needed it -- it was that safe."
Date of death: 9/20/97
Remarks on Dog's Rimadyl Experience: "When I inquired about Rimadyl in July 1997, it was after seeing a TV commercial. At that time, there was NO disclaimer at the end of the ad.  For the first few weeks on Rimadyl, Savannah seemed better.  She got around more easily and was able to walk with me, swim, chase her frisbee, etc.  When she lost her appetite after about a month, I thought it was due to a recurring ear infection.  Since I had been given such a glowing recommendation about the safety of Rimadyl, I never suspected it might be the cause.  I had even asked about any liver side-effects and was told 'No, absolutely not.' After 2-3 days, she began eating again and for the next couple of weeks, she was fine. On Friday, September 19, 1997, she began acting bad again.  On Saturday, the 20th, she was very lethargic.  She would even go off by herself, which was VERY out of character.  I still didn't suspect the Rimadyl--even if I had, it would have never occurred to me that she was actually dying right before my eyes.  That evening, I suddenly couldn't find her anywhere.  When I finally discovered her, she had gone into my shower in the bedroom and was cold as ice, and barely breathing.  We rushed her to the vet; she lasted about 2 minutes after we got her inside.  Needless to say, I was devastated and totally confused.  It didn't take long for me to figure out what had happened.  I reported the death to the prescribing Vet and also to Pfizer.  I refused to have her autopsied; we'd all been through enough, and there is no doubt in my mind as to what she died of.  I'm appalled that the lives of these animals and the hearts of their owners are being sacrificed on the altar of Pfizer's bottom line.  The next time I saw the ad for Rimadyl, there was a disclaimer at the end, warning of side effects.  Too little, too late for Savannah.  I still miss her; she was my best girl for nearly 6 years."
beaner@aug.com

8/9/99 Death #59: Vets' Disagreement Causes Delay in Treatment and Fatal Result
Breed: Terrier Mix (female, "Soda")
Age: 13 years
Reason for Rimadyl rx: arthritic condition
Dog's weight and dosage taken: 40 lbs, 50 mg 2x daily
When reaction occurred following initial dose: 2 weeks
Symptoms: inappetance, vomiting
Date of death: July 9, 1999
Vet informed about side effects: NO; absolutely not!
Remarks on Dog's Rimadyl Experience: "After two weeks on Rimadyl, Soda exhibited some seemingly minor symptoms. She was eating less than usual (which we attributed to some dental work done on June 10). Then on June 23, she began to vomit occasionally. We took her into the Veterinary Clinic on June 24. Ironically, one of the two veterinarians we saw commented that it wasn’t likely to be the Rimadyl causing Soda’s symptoms. One of the veterinarians requested blood work; however, the senior veterinarian overruled that suggestion and we were sent home. Soda continued to vomit and I took her back the next day. She was then hospitalized with IV fluids; the diagnosis was 'liver necrosis.' We were told it was a 'rare' side effect of Rimadyl. What followed was a fiasco of incompetence and delays. We ended up changing veterinarians over it. Soda did better with our present veterinarian. She seemed to go into a remission that lasted four days. Then the vomiting returned and we took her back for more IV fluids and treatment. We watched helplessly as our beloved Soda’s bright spirit faded. She was not able to fight the toxic effects of Rimadyl. In the end, we assisted Soda by way of euthanasia."
fineline@telusplanet.net

9/19/99 Update on Death #59 -- Autopsy Report Establishes Rimadyl Toxicity as Cause of Death
Excerpts from Soda's necropsy report: "The liver was small and diffusely mottled red/white. The cut surface of the liver had a similar appearance. . . . All sections of the liver are similar in revealing widespread degeneration and necrosis with variable inflammation. The changes are uneven in their severity with large areas affected by complete necrosis ... " Veterinarian Dr. Less McCurdy stated, following a review of the necropsy report: "The fact that Soda's liver enzymes on June 10, 1999, were normal would rule out any pre-existing liver disease. This combined with the necropsy report provides compelling evidence of a Rimadyl toxicity."

8/8/99 Death #58: Dog Reacts to Dosage Increase after Five Months on Rimadyl; Is Euthanized
Breed: Labrador/Terrier Mix (female, "Te'y," short for "Teddy")
Age: about 12 years
Reason for Rimadyl rx: Had recently developed arthritis and shaky legs
Dog's weight and dosage taken: about 70 lb, 75 mg 2x daily
When reaction occurred following initial dose: negative signs about 5 months after first dose
Symptoms: lethargy, vomiting, depression (not really herself), inappetance, panting, minimal exercise caused exhaustion, refusal to stand, yellow eyes, bloating, eating rocks; liver and kidney enzymes skyrocketed
Date of death: August 7, 1999
Vet informed about side effects: NO; she never informed us of any. We asked her the night before our Te'y was euthanized if Rimadyl caused the liver and kidney failure, and she assured us it didn't.
Remarks on Dog's Rimadyl Experience: "When we first began Rimadyl, it seemed like a miracle. Te'y had energy that seemed to come out of nowhere. The shaking in her legs stopped, and her arthritis seemed non-existent. Since she was doing so well, after a couple of months, we decided to drop her dosage to once per day. Then she began getting shaky and didn't enjoy her walks. The vet told us to go back to twice per day. That was a week before her death. After we returned to two doses per day, she stopped eating, and all of the above symptoms appeared quite suddenly. Her last night she began vomiting what little food she ate. We rushed her to the vet; the diagnosis was liver and kidney failure. Her body was filled with toxins, which made her eyes yellow. She was in a great deal of pain. The vet said she would keep her there overnight to make her as comfortable as possible. The next morning we returned to the vet's office and had her put to sleep. It was the only thing we could do for her. That same night I found the reports on Rimadyl and was struck by how similar other stories were to Te'y's experience. Even though the vet now says Te'y's death wasn't from Rimadyl because, unlike other cases, her liver was enlarged, I still can't believe there was no connection. Her symptoms fit too perfectly. I believe her death could have been prevented if the vet had told us about this. But now it is too late. There never will be another Te'y. I would like to to add that I understand Rimadyl works wonders for many dogs. I wouldn't want to discourage people from using it, but I would encourage them to be informed about the possible side effects."
terrylumsden@sprintmail.com

8/6/99 Death #57: Vet Makes Diagnosis of Gastric Torsion; Necropsy Shows Symptoms Consistent with Toxic Reaction to Rimadyl
Breed: Chow Mix (female, "Maggie Mae")
Age: 5 years
Reason for Rimadyl rx: pulled ligament
Dog's weight and dosage taken: 70 lb, 75 mg 2x daily
When reaction occurred following initial dose: 4 weeks
Symptoms: violent vomiting; inappetance; paralysis on last day of her life
Date of death: July 18, 1999
Vet informed about side effects: NO; insisted Rimadyl could not cause side effects
Remarks on Dog's Rimadyl Experience: "Maggie was in very good health until Rimadyl. A week before she died, her appetite diminished. We thought it was due to the hot weather. When she began vomiting violently, I called our vet, who told me to give Maggie Pepto Bismol. She vomited that as well a short time after we gave it to her. I asked the vet if he thought Rimadyl could be the cause. He said, 'No way.' Maggie seemed to be getting progressively weaker, so on Sunday morning, we drove her 35 miles to the emergency clinic. Her blood pressure was so low, they couldn't even get a blood sample from her. The emergency clinic vet really worked to save her, but, at 4:00 that afternoon, Maggie died. I had been a loyal client of my vet for 30 years, but he's lost me now. He kept insisting that Maggie's death was caused by gastric torsion until the necropsy report came back. He finally called to tell us that the necropsy showed the kind of evidence that is consistent with Rimadyl toxicity. We miss Maggie so much. We raised her on a bottle. There will never be another Maggie."
phoneswa@zebra.net

8/6/99 Correction/Update to Death #19: Abby, Only 5 Years Old, and One of the First to Die of Rimadyl Toxicity; Case Shows Rimadyl Can Be Fatal to Dogs with Undersized Liver
Breed: Black Lab (female, "Abby")
Age: 5.5 years
Reason for Rimadyl rx: wrist injury
When reaction occurred following initial dose: 2 weeks during first episode; 2 days during second episode that resulted in death
Symptoms: vomiting; inappetance; listlessness; elevated liver enzymes
Date of death: July 14, 1997
Vet informed about side effects: NO; did not suspect Rimadyl in first episode, so prescribed again
Remarks on Dog's Rimadyl Experience: "What my vet and I did not realize was that the vomiting and lack of appetite were related to liver dysfunction brought about by a toxic reaction to

7/16/99 Update to Death #42:
Suspect Only 10% of Deaths from Rimadyl Are Reported
"Many vets I know have changed their screening procedures and follow up due to Eliza's and other Rimadyl-related deaths.  At the kennel I use, of a total of 8 or 9 dogs on Rimadyl, all but one died not long after being put on the drug. None but Eliza's have been reported. This leads me to suspect that only about 10% of the actual deaths from Rimadyl are being reported.  It has been eight months since Eliza's death; I will never forget. It was such a violent, horrible death. Along with many people I know, I have turned to acupuncture, chondroitin sulfate, glucosamine, vitamins C and E and chiropractic treatment -- and away from prescription drugs."
Breed: Greyhound (female, "Eliza Jane")
Age: 9 years 9 months
Reason for Rimadyl rx: suspected pinched nerve
When reaction occurred following initial dose: 5 weeks
Symptoms: bruising, blood in ear, vomiting and urinating blood (progressive over 5 days)
Date of death: November 9, 1998
Vet informed about side effects: Vet is as informed as possible--told me about possible liver problems, initial blood work done
Remarks on Dog's Rimadyl Experience: "Necropsy results in short: no bone cancer; hemolytic anemia (drug induced cannot be ruled out).  One vet at Pfizer said she sees two of these a month.  How many more go unreported? It seemed to be no big deal to her.  Two a month is small compared to how many dogs take this medication is what I was told.  Well, it is a big deal to me. I am dismayed by the lack of concern of vets who attribute deaths and reactions to old age, or simply tell their distraught clients that tests to prove Rimadyl was the cause are too expensive. If I was in their place, I would pay for the tests. As a health care provider, I would want to know if a drug I was prescribing did have these kinds of side effects. I have heard from the vets that updates they receive from Pfizer downplay side effects. I think Pfizer needs to be responsible in giving drug information to the vets, and should provide printed material for the vets to give to owners of dogs receiving this drug."
Burpdog@email.msn.com
This is an abbreviated report; complete report available upon request to: rimreport@srdogs.com

7/16/99 Correction/Update to Death #19: Abby, Only 5 Years Old, and One of the First to Die of Rimadyl Toxicity; Case Shows Rimadyl Can Be Fatal to Dogs with Undersized Liver
Breed: Black Lab (female, "Abby")
Age: 5.5 years
Reason for Rimadyl rx: wrist injury
When reaction occurred following initial dose: 2 weeks during first episode; 2 days during second episode that resulted in death
Symptoms: vomiting; inappetance; listlessness; elevated liver enzymes
Date of death: July 14, 1997
Vet informed about side effects: NO; did not suspect Rimadyl in first episode, so prescribed again
Remarks on Dog's Rimadyl Experience: "What my vet and I did not realize was that the vomiting and lack of appetite were related to liver dysfunction brought about by a toxic reaction to Rimadyl. Abby came through that episode and returned to normal, as far as we knew. When she reinjured the wrist in early June, I gave her the Rimadyl for two days and the vomiting began again. I thought she had an upset stomach. Unbeknownst to me and my vet, Abby was born with a liver that was too small for her body. This is why she had the fatal reaction to Rimadyl. This birth defect (an undersized liver) is common, and Rimadyl can be fatal in those animals in which it appears. My vet told me that it is very hard to know if a dog has an undersized liver. Liver function blood panels will show normal levels, as was the case with Abby when she had her annual exam one month before starting on Rimadyl. The only way to be certain of the liver size is to have an ultrasound performed and, unfortunately, that is only done when a problem appears."
LMOORHD@aol.com

7/15/99 Dog Is Euthanized Following Liver Toxicity
Breed: Spaniel/Border Collie mix (female, "Jipsy")
Age: 12 years
Reason for Rimadyl rx: arthritis
Dog's weight and dosage taken: 55 lbs; 50 mg/2x daily; subsequently reduced to 25mg every other day
When reaction occurred following initial dose: not specified
Date of episode: not specified
Symptoms: liver toxicity detected by blood tests
Date of death: 7/14/99
Remarks on Dog's Rimadyl Experience: "Jipsy was euthanized yesterday. 7/10/99 blood test measured alk phos - 7440 (normal range 5-131), creatinine- 2.8 (normal range 0.5-1.6). 7/14/99 levels were alk phos - 10490, creatinine - 8.6. Autopsy determined kidneys appeared nearly normal; liver was grainy and gristly with scar tissue, but contained no apparent tumors."
5/21/99 Case #68: Liver Toxicity Detected While on Rimadyl
Remarks: "My dog was both overweight and arthritic. My veterinarian prescribed thyroid medication and Rimadyl. Follow-up bloodwork showed improved thyroid levels but also detected liver toxicity. We withdrew Rimadyl, and her liver levels returned to normal. However, her arthritis worsened. I was instructed to resume Rimadyl as before, but have chosen to give her 25 mg every other day instead. She also gets a Cosequin tablet daily and sleeps on a special mat. She's lost 20 pounds, her energy level is good, and she moves more easily, but is still stiff on arising."
kbheaton@swbell.nett

6/10/99 Death #56: Kidney Failure Potentially Linked to Rimadyl; Dog's Quality of Life Improved, but Informed Choice Remains an Issue
Breed: Mixed Sheltie & Terrier (male, "William")
Age: 15 Years
Reason for Rimadyl rx: .shoulder socket too big for femur head
Dog's weight and dosage taken: 28 lbs; not sure of dose
Length of time on Rimadyl: 8 months
Symptoms: total renal shutdown; highest protein levels vet had ever seen in a living dog
Date of death:.May 6, 1999
Did vet seem informed & inform you about side effects?: Mentioned potential stomach problems; disputed my concerns about other symptoms
Remarks on Dog's Rimadyl Experience: "I was advised by my vet to put William on Rimadyl to relieve his joint discomfort (which really was quite bad). After he was on it for 8 months, I had William back to the vet for a check up and the vet stated his protein was high at 75; normal was around 15 - 20. He placed him on IV's to flush him out. The vet told me the diet I was feeding William was too rich in protein and specifically red meat. He put him on some awful dried dog food that William would not eat. I forced him to live on that diet for two months then allowed him to return to a normal diet. In May he became lethargic. I was afraid he was just getting old quickly. Over the period of two weeks he got progressively worse. I was already questioning the capability of my vet from past visits. I had to go out of town and my sister (a nurse) kept William. By this time he had stopped eating altogether. She forced fluids and he seemed to stabilize. On Wednesday he got worse and she took him to her vet. When he arrived, the vet placed William on IV's and began running tests. Within two hours, William had a seizure and died. I told the vet when I went to pick him up that I felt William had been poisoned with the Rimadyl. He said he checked the Internet and that the drug was absolutely not the cause. There was NO documented proof that Rimadyl had any severe side effects, he said, and that people who had spread this information were misinformed and had misused the Internet data." (Coordinator's note: Pfizer literature about Rimadyl clearly cites renal effects.) "I feel terribly guilty. I put William on the drug to enhance his quality of life; and it did. I wish however that someone would have informed me of the severe side effects so that I could have made a more informed decision. I don't really know if I had it to do over again whether I wouldn't still give him the drug, but I would have monitored the side effects more closely. I firmly believe that quality of life is more important than quantity, but informed decisions are critical when dealing with a beloved pet."
RMWATL@AOL.com

5/28/99 Death #55: No Warning of Rimadyl's Side Effects Given to Family of 3-Year-Old Newfoundland
Breed: Newfoundland (male, "Yukon")
Age: 3 years
Reason for Rimadyl rx: limping after romp with older brother
Dog's weight and dosage taken: 140 lbs, 300 mg daily
When reaction occurred following initial dose: 6 weeks
Symptoms: inappetance, vomiting (food and water), black tarry stools, urinating in house, change of daily habits (where he slept), difficulty climbing steps, lethargy
Date of death: May 28, 1999
Did vet seem informed & inform you about side effects? No. He gave us no indication whatsoever there were any adverse effects related to Rimadyl.
Remarks on Dog's Rimadyl Experience: "The symptons were subtle, yet we knew something was not right. We called the vet the third day or so of vomiting. He told us to administer Pepto Bismol, and, if there was no improvement, to come into the office in the morning. In the morning, Yukie was dead. In all, it was about a week that he wasn't 'up to snuff.' The vet did a preliminary autopsy and said that, in 30 years of practice, he had never seen a liver like it -- 1/4 to 1/3 of the size it should be, pitch black and covered in nodules. This was a healthy, beautiful animal just two months ago who was reduced to his final days in confusion. I don't need to tell you the void he's left. I cry my eyes out missing him. We were NEVER told of ANY side effects of this RIMADYL. Had we been told that there was even a slim chance of liver damage, we would NOT have given it to him. It wasn't worth the risk when compared to a limp we felt would eventually go away. We damn ourselves as well as Yukie's vet. But, in all honesty, we realize the vet may not have known. Our much-loved boy is gone - nothing will bring him back. PLEASE, please, please mark RIMADYL off your list of drugs for a faithful companion. I would not wish the heartache and self-doubt that we've felt on anyone." Update June 7, 1999: The lab report on Yukon's liver was not definitive. Neither the attending vet nor Pfizer can identify Rimadyl as the cause of Yukie's death. The Pfizer vet suggested that the dog may have had a pre-existing condition that was exacerbated by taking Rimadyl and has offered Pfizer's help in covering the expenses associated with his death.
mwdwrd1642@aol.com

5/13/99 Death #54: Dog Is Euthanized Following Toxic Reaction to Two Doses of Rimadyl; No Baseline Tests Done; No Side-Effects Warning Given
Breed: Golden Retriever (male, "Jamie")
Age: 14 1/2 years
Reason for Rimadyl rx: arthritis, lameness
Dog's weight and dosage taken: 75 mg prescribed 2x daily
When reaction occurred following initial dose: after two doses
Symptoms: heavy panting; paralysis; neurological damage; seizures
Date of death: May 12, 1999
Did vet seem informed & inform you about side effects? "I was not given any information about the drug by the vet, and no baseline tests were performed."
Owner's Comments: "I am heartbroken. My Golden Retriever, Jamie, had to be put down yesterday. He was prescribed Rimadyl for arthritis. He had 2 doses of 75 mg. each, one on Monday night and one on Tuesday morning. On Tuesday morning, I noticed that he went to his water bowl for his usual morning drink, but turned away and walked back to sleep some more. We then went for our daily morning walk. I was pleased to see that he actually swam a little in his favorite pond; his recent lameness had made him a little reluctant to trust himself in the water. I thought that perhaps the Rimadyl was already helping. I left for work at about 12:30; when I returned five hours later, Jamie was panting heavily and could not get up. His front legs were stiff and his rear legs were flacid. I called the vet who had prescribed the Rimadyl and was told he had probably just overdone his exercise. I took him to an animal hospital in another state (we live in Vermont) and was told he was suffering from neurological damage and seizures, and the kind thing to do would be to put him down. I was told he was in a lot of pain. There were x-rays taken. They revealed that Jamie had a tumor in his spleen and one in his lung. I knew his prognosis was not good anyway and so agreed reluctantly to have him put to sleep. I just can't believe that two mornings ago, my dog was swimming and rolling around in the grassy meadow in the beautiful spring sunshine, and now he is gone. I believe that Rimadyl caused the seizures and neurological symptoms. I know Jamie wouldn't have lived a good deal longer with his cancer, but he was so panicked by the fact that he could not get up. His death was so traumatic for me; it is a nightmare that I just can't get over, especially since I didn't know about the side effects of the drug. I feel as though I killed him with my ignorance. I am just so hurt and angry that my good companion had to die in such a terrible way, and that I let him down."
GretchenMcCabe@mail.newsbank.com

5/13/99 Death #53: Rimadyl Suspected in Death of Doberman; No Baseline Tests Done; No Side-Effects Warning Given
Breed: Doberman (female, "Gracie")
Age: 13 years
Reason for Rimadyl rx: trouble climbing stairs
Dog's weight and dosage taken: 75 mg 2xdaily
When reaction occurred following initial dose: 3 weeks
Symptoms: inappetance; refusal to drink; paralysis; liver and kidney failure; internal hemorrhaging
Date of episode/death: April 8 - May 4, 1999
Did vet seem informed & inform you about side effects? no baseline tests done; no warnings given of side effects
Owner's Comments: "My father's dog, Gracie, was a healthy 13-year-old Doberman with no major health problems.  On 4/8/99, my father took her to the vet for her annual check-up. Everything was fine, except that she was having some trouble with her hind legs, going up and down the stairs.Vet gave Rimadyl 75mg. twice a day for one week but did not take blood work or describe any side effects. On 4/13/99, due to improvement in Gracie, my father bought enough Rimadyl for 30 days. The vet felt that she probably had a pinched nerve. On 4/30/99, Gracie had trouble getting up from a lying position and would not eat or drink. My father called the Vet and was immediately told to stop the Rimadyl and to bring her in the next day. On 5/1, Gracie needed to be carried to the vet, where she was admitted, put on IV fluids. Bloodwork was done and X-rays taken.  On 5/3, when my father went in to visit Gracie with her favorite food, she still would not eat or drink. My father questioned the Vet about Rimadyl toxicity and he stated that he did not think that was the problem.  On 5/4, the Vet called my father at 7:30 to inform him that Gracie's condition had deteriorated rapidly, there was blood in her urine, and she was going into liver and kidney failure. He said that her condition was very poor and chances of recovery were not good and recommended euthanasia. We went to get Gracie and transferred her to a large teaching animal hospital close to our home, for a second opinion. By the time we got there, we believe it was too late. I informed this Vet that we strongly suspected Rimadyl toxicity. He told us that at that point she was bleeding internally with no clotting at all, and she was in complete liver and kidney shut down. Both the blood pressure and temperature were very low. The Vet recommended euthanization, and we agreed. Gracie died on 5/4/99. It was on 5/1/99, that I found this website and could not believe how many of the incidents were so similar to Gracie's."
nlp1752@earthlink.net

5/2/99 Update on Death #7: Owner of Dog Who Died from Rimadyl Toxicity Now Works as a Vet Tech
"After losing my dog, Deter, to Rimadyl toxicity, I quit a business management position and became a vet tech so that I could learn more about the care of animals and about drug reactions. Deter became ill May 26, 1997, and died a month later. feel like I killed him because I was uninformed. The clinic I work for is a state-of-the-art facility. I was very impressed, and even during my interview I told about my experience with Rimadyl. I was told that such a reaction was very, very rare; the clinic had never had a dog have a reaction. Subsequently, I saw at least half a dozen dogs come in exhibiting sudden inappetance, swollen abdomen, kidney and renal failure, anemia, etc. Every one of these dogs was on Rimadyl, yet not once did any of the doctors consider Rimadyl to be a cause. Their reaction was, 'That's strange; there seems to be some type of abdominal or spleen mass.' The dogs either died or were euthanized. When I asked about possible Rimadyl reactions, I was told 'Pfizer has not contacted us in reference to side effects. We have never received official notice from Pfizer on this.' It is clear that they still haven't received any, since just last week I had my Lab/St. Bernard Mix in for toenail removal. They prescribed Rimadyl for pain without giving it a second thought! I had tried Rimadyl for him before on the recommendation of a very good friend who is a vet. Within 8 hours, he suffered labored breathing and had become aggressive. Needless to say he did not receive any more of it. "
BArring370@aol.com

5/2/99 Update on Death #3: More Comments from Owner of Dog Who Died from Rimadyl Toxicity
"The following is a link to the Pfizer PetNet site and product information about Rimadyl. The side effects are listed. Don't vets read them?

http://www.petnet.com/rimadyl/info.asp

"We had been managing my dog's aging kidneys for two years with diet and hydration with good results. I specifically asked about Rimadyl's side effects on her kidneys and was told by my vet that Rimadyl was processed in the liver. After reading more about Carprofen and its effect on the kidneys, I again mentioned it to the vet. He repeated the same thing -- only this time, he sounded a bit irritated. All the symptoms I subsequently reported to him were attributed to age. With what I know today, I would not put any elderly dog on Rimadyl. The biggest risk factor for any NSAIDs is age. Euthanasia would have to be the only alternative for me to use Rimadyl."
bjsinclair@earthlink.net

4/26/99 Death #52: Chow Turns Aggressive Toward Owner; Is Euthanized Following Suspected Toxic Reaction to Rimadyl
Breed: Chow (male, "Winnie the Pup")
Age: 5 years, 4 months
Reason for Rimadyl rx: arthritis, hip dysplasia
Dog's weight and dosage taken: 62 lbs; 100 mg initially; 50 mg for short period; 100 mg at time of death
When reaction occurred following initial dose: almost immediately; owner tried withdrawing drug, but vet maintained it could not cause the symptoms dog was exhibiting, so drug was continued
Symptoms: severe diarrhea, listlessness, inappetance, confusion, exhaustion, severe digestive problems
Date of episode/death: Died April 15, 1999
Did vet seem informed & inform you about side effects? NO!! NEVER!!
Owner's Remarks: "The vet put him on regimen after regimen of antibiotics. He told me that he had colitis. Winnie was also getting Adequan injections every 2 or 3 months which worked great until Rimadyl was added. The vet put him on Canine I/D diet and had me take him off wet food and withdraw treats. Winnie was so depressed. I got a second opinion and the next vet increased his Rimadyl dose to 100mg and gave him a wormer, even though Winnie's worm test were negative. Vet said that parasites don't show up on worm tests. I told the vet that I didn't like the way I thought Rimadyl was affecting my dog, and they told me that it WAS NOT THE DRUG! Winnie the Pup was diagnosed with hip dysplasia when he was a puppy. He had two torn ligments in his knees and had two knee surgeries about a year apart. He did great and recovered quickly. As he got older, he started getting a little stiff, especially at night, so the vet prescribed Rimadyl. He was on 50mg. I immediately noticed that he became lethargic and depressed. I took him off the drug because he was so unhappy. The next vet visit, the vet told me that the Rimadyl was not the cause and he put him back on it. Winnie started to have chronic diarrhea and went downhill fast. He became confused on his walks and started to limp. The whites of his eyes were not white. On Easter Sunday 1999, I was sitting on the floor playing tug with Winnie. Suddenly, he growled and attacked me. He bit one side of my nose completely off. He had never exhibited aggressiveness of any kind in his entire life. I have had to have reconstructive surgery (a six-hour operation). But, worst of all, Winnie had to be put down while I was in the hospital. After the attack, he didn't even recognize my sister. I AM DEVASTATED at the loss of my dog. NO ONE EVER told me of the potentially dangerous side effects of Rimadyl. This lack of information has cost the life of my dog and has left me with permanent physical and emotional scars. I have contacted Pfizer and told them I want it to be mandatory that all vets across the country print out a sheet with all the side effects and tests that are recommeded while the animal is on the drug. And I'm not the kind of person that will let it rest. I don't want anyone else to suffer the way that I have. I feel that I killed my dog with this drug. Anyone is welcome to write to me."
dudette181@webtv.net

3/4/99: Death #51:
Collie with History of Ulcer Is Given Rimadyl
Breed: Collie (female, "Honey")
Age: 11 years
Reason for Rimadyl rx: arthritis pain
Dog's weight and dosage taken: 90 lbs./100 mgs. 2X day
When reaction occurred following initial dose: drug had been administered intermittently over several months
Symptoms: seizures, diarrhea, rash; anemia, internal bleeding
Date of death: 7/29/98
Vet informed about side effects?: Vet insisted symptoms were due to old age; said Rimadyl could not cause stomach upset or digestive distress
Owner's Remarks: "The summer prior to my dog's being given Rimadyl, she had a duodenal ulcer. I almost lost her due to the bleeding. She spent a week at the ICU at Purdue vet school clinic. From then on, we had to be very careful about what medicines she could take for her arthritis. Rimadyl was recommended because, I was told, it would not cause stomach upset or digestive distress. She had been on Rimadyl on and off for a few months. It was withdrawn due to a high fever and rash that developed. What is puzzling is that her bloodwork showed normal levels five days before she died of anemia. Within 3 hours of developing symptoms, she was unresponsive. I repeatedly asked if Rimadyl could be causing this and was told, 'No; its due to old age.' I have not gotten over Honey's death. Eleven years is not old to me. I've had Irish setters live to be 17. Honey was too young, and I blame Rimadyl for her suffering and for her death."
jmcniven@netnitco.net

Death #50:
Collie Dies of Liver Toxicity; No Baseline Tests Done
Breed: Collie (male, "Logan")
Age: 7-8 years
Reason for Rimadyl rx: arthritis pain
Dog's weight and dosage taken: 78 lbs./100 mgs. 2X day
When reaction occurred following initial dose: 6 weeks
Symptoms: Loss of appetite, vomiting, excessive panting
Date of death: 12/28/98
Vet informed about side effects?: Vet who prescribed Rimadyl said there were few -to-no known side effects
Owner's Remarks: "Logan went off his feed Friday evening. Saturday evening, he still refused to eat, and later began vomiting. He died sometime during the night on Monday. Our vet (NOT the one who prescribed Rimadyl) is very hesitant to identify Rimadyl as the culprit, but took my suspicions seriously enough (Logan died of liver toxicity) to call a staff meeting and begin doing preliminary blood work before prescribing the drug in the future. For that I am quite thankful. I suspect that Logan may have already had some type of liver irregularity or disease prior to taking the drug, which predisposed him to the reaction he had, but I can't help but wonder if some preliminary blood work would have revealed that. We lost a very-much-loved family friend. Just wish I'd have done more homework before putting him on it."
mmkarner@iolok.com